Levitra® (vardenafil hydrocoride trihydrate) was co-developed by Bayer Pharmaceuticals and Glaxo Smith Kline as a challenger in the competitive male impotence pill market that has been dominated by Viagra® since its launch in 1998. They are all PDE-5 inhibitors that relax the muscles and blood vessels in the penis, resulting in a natural erection.

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PDE5 inhibitors help the body's natural response to sexual stimulation, since they block the enzyme Phosphodiesterase-5 in the smooth muscle cells in the penis.

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